Marine oil spills represent one of the most catastrophic environmental disasters, devastating marine ecosystems and coastal communities worldwide. Traditional chemical dispersants, while effective at breaking down oil slicks, often introduce additional toxicity to already damaged marine environments, creating long-term ecological harm. The development of fish waste based biodegradable dispersants bridges the gap between marine pollution management and sustainable resource, these natural compounds effectively break down large oil slicks into smaller droplets, accelerating their natural degradation by marine microorganisms without introducing harmful toxins into the environment shows eco-friendly alternative that combine biodegradability, safety, and efficiency while minimizing ecological toxicity. This not only provides a sustainable solution to the environmental hazards of oil spills but also valorizes fishery by-products, aligning with the principles of circular bioeconomy and waste-to-wealth conversion.