Due to its zoonotic potential, Avian Influenza (AI), also referred to as bird flu, continues to pose a serious threat to the health of poultry, rural livelihoods, and public health worldwide. AI is caused by influenza A viruses and is naturally found in wild aquatic birds. It can be either low pathogenic (LPAI) or highly pathogenic (HPAI), with the H5N1 and H7N9 strains being the most dangerous. Contact with infected birds, contaminated feed, water, or equipment is the main way that the disease is spread, and poultry suffer from severe illness and high mortality rates. Although infections in humans are uncommon, there is a risk of occupational exposure, and viral mutations may lead to pandemics. Due to culling, trade restrictions, and consumer anxiety, outbreaks cause significant financial losses that disproportionately impact small farmers and the security of the nation's nutrition supply. Effective control requires strict biosecurity, surveillance, culling, and awareness, complemented by research and government interventions. In order to protect both people and poultry, avian influenza is an example of a One Health issue that calls for cooperation between veterinarians, farmers, researchers, public health organizations, and the community.