Climate change significantly influences plant disease dynamics, increasing the frequency and intensity of outbreaks. Historical events, such as the Irish Potato Famine and Bengal Famine, highlight the devastating impacts of plant diseases under conducive environmental conditions. Modern climate variability, including rising temperatures, erratic rainfall, and increased atmospheric CO2 levels, alters host-pathogen interactions and exacerbates disease severity. This article discusses these challenges and their impact on plant diseases dynamics. It also explains ways to manage these challenges using chemical, biotechnological, biological, technological, and cultural methods. By integrating forecasting tools and sustainable practices, these methods aim to strengthen resilience against climate-induced plant diseases and support farmers in mitigating their impact effectively.