This article highlights the essential roles of Geographic Information Science (GIS) and remote sensing in addressing natural resource and environmental challenges. It emphasizes the integration of big data and artificial intelligence to enhance applications in these fields. Key components such as geo-modeling and geo-analysis are discussed alongside advancements in remote sensing technologies. The paper explores various applications, including agriculture, soil science, water resource management, and disaster management, underscoring the need for innovative methodologies and multi-source data integration to tackle pressing global issues like climate change and resource mismanagement.