Biofortification is a leading-edge strategy to boost the nutritional value of crops, thereby addressing global malnutrition challenges. It not only tackles food insecurity but also improves the economy of the country. Agronomic biofortification can be an important tool in combating malnutrition and achieving nutritional security. In recent hours its importance has increased because of limited access to nutritious foods and climate change-related issues. It is a means of increasing the bioavailability of nutrients in plants and plant products by use of befitted fertilizer form, application method, and time of application. The significance of agronomic biofortification for global nutrition and food security has been underscored by recent technical advancements and an increasing awareness of mineral micronutrient nutrition.