Biologically active compounds used in agriculture that develop near aquatic environments easily spill into rivers or other aquatic system. Pesticides have been found to be highly toxic not only for fish but also to the other organisms which constitute the food chain. Bioaccumulations of these pesticides danger the long-term survival of fishes by disrupting the ecological relationships between organisms and diversity loss. Insecticides, herbicides and fungicides are observed worldwide in aquatic environments and accumulated in aquatic organism. Many insecticides, including organochlorine and organophosphate, have long been banned long ago because of their high persistence and non-target toxicity. Pesticides Effect on hemato-biochemical parameters and histopathology of several important organs of fish.