Punica granatum, popularly referred to as pomegranates, belongs to the Punicaceae monogeneric family and is primarily found in Iran. It is the most adaptable subtropical fruit crop, introduced to India in the fifteenth century from the Mediterranean region. Maharashtra, Gujarat, Karnataka, Andhra Pradesh, Tamil Nadu, Madhya Pradesh, and Rajasthan are the states where it is grown for commercial use. It contains significant phytochemical elements such as ellagic acid, ellagitannins, Punic acid, flavonoids, anthocyanins, estrogenic flavonoids, and flavones, it has a wide range of therapeutic applications. Treatments for ulcers, snakebites, liver damage, dysentery, diarrhoea, helminthiasis, acidosis, bleeding, and respiratory issues have all been linked to these ingredients. Additionally, sustainable farming methods that emphasize agronomic breakthroughs that improve pomegranate crop quality, productivity, and environmental resilience. Pomegranate nutritional integrity and biodiversity are mentioned as being strongly correlated with the use of organic and environmentally friendly farming practices. Pomegranates are becoming recognized as an important resource for improving both sustainable farming methods and human health. This review summarises all the cultivation practices, the bioactive components of pomegranates, and their nutritional qualities as functional foods, focusing on the fruit's peel, seed, and aril byproducts.