The Viksit Krishi Sankalp Abhiyan (VKSA)-2025 envisions a modern, self-reliant, and inclusive agricultural sector in India, where technology, sustainability, and farmer empowerment converge to drive rural prosperity. Livestock, a critical pillar of Indian agriculture, contributes significantly to household income, nutrition, and women empowerment particularly among smallholder and marginal farmers. However, despite India?s global leadership in milk, meat, and egg production, productivity per animal remains low due to genetic limitations, unscientific breeding practices, and underutilization of indigenous breeds. This article explores how targeted interventions in Animal Genetics and Breeding including selective breeding, genomic selection, and indigenous breed improvement, can address these challenges and align seamlessly with VKSA-2025 goals. Emphasis is placed on enhancing peranimal productivity, promoting Atmanirbhar Bharat through native germplasm, building climate-resilient herds, and creating inclusive livestock-based microenterprises involving women and youth. By integrating scientific breeding strategies with grassroots implementation, livestock genetics can emerge as a powerful tool to transform rural livelihoods and accelerate the realization of a Viksit Bharat.